Mn-DPDP Enhanced T1-weighted Magnetic Resonance Cholangiography: Usefulness in the Diagnosis and Roadmap for the Treatment of Intrahepatic Choledocholithiasis

cholangiography is a noninvasive modality that has been proven accurate in the diagnosis of bile duct obstruction and choledocholithiasis (1, 2). Previous reports concerning the usefulness of MR cholangiography for the assessment of intrahepatic choledocholithiasis have focused on the presence of intrahepatic ductal dilatation, stricture, and calculi (3, 4). However, heavily T2weighted MR cholangiography cannot reflect biliary dynamics. Mangafodipir trisodium is a safe and approved hepatocyte-selective T1-weighted MR contrast agent, eliminated through the biliary system, and can therefore, in theory, be used as a biliary contrast agent during T1weighted MR imaging (5-8). To our knowledge, however, the potential role of this agent in the evaluation of inJ Korean Radiol Soc 2004;50:353-357